Several members of the cast participated in adaptations of comic book and/or graphic novel adaptations outside of the Marvel Cinematic Universe: Scarlett Johansson appeared in Ghost World (2001), The Spirit (2008), and Ghost in the Shell (2017). Chris Evans appeared in I Fantastici 4 (2005), I Fantastici 4 e Silver Surfer (2007), TMNT (2007), The Losers (2010), Scott Pilgrim vs. the World (2010), and Snowpiercer (2013). Powers Boothe (who provides a cameo in the film) appeared in Sin City (2005). Alexis Denisof appeared in several DC productions beforehand. Samuel L. Jackson appeared in The Spirit (2008).

Film

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